The Theory of Aging

With Dr Brian Dixon

What is Protandim Nrf2?

Nrf2 is a powerful protein that is latent within each cell in the body, unable to move or operate until it is released by an Nrf2 activator. Once released it migrates into the cell nucleus and bonds to the DNA at the location of the Antioxidant Response Element (ARE) or also called hARE (Human Antioxidant Response Element) which is the master regulator of the total antioxidant system that is available in ALL human cells.

This balancing act can become disrupted as one ages, or if the body is overcome by malfunction and disease resulting in further cellular damage. This damage is known as oxidative stress and is accompanied by free radical production. Oxidative stress and the associated free radical damage contributes to the progression of hundreds of conditions and aging symptoms.

Direct antioxidants

Direct antioxidants such as vitamin C, Vitamin E, berries and juices have typically been used to neutralize free radicals and to prevent the damage they cause. One molecule of antioxidants from these sources neutralizes one free radical, i.e. they combat free radicals on a one to one ratio. However there comes a tipping point where the direct antioxidants are inadequate to take care of the damage.

One to one million ratio

A better approach to fighting free radicals is to use the body’s own self defense mechanism. When Nrf2 is activated in the nucleus, it turns on the production of antioxidant enzymes such as Catalase, Glutathione Peroxidase and Superoxide Dismutase (SOD). These antioxidant enzymes are powerful enough to neutralize up to one million free radicals . This million to one ratio proves to be a much more effective approach in combating aging and conditions.

Protandim Nrf2 activators

Since the Nrf2 protein remains dormant in a cell until it is activated by a Nrf2 activator. The challenge is to determine what activates Nrf2 to take advantage of the one to one million free radical neutralization mentioned above?

Nutrigenomics

Powerful Activators of the Nrf2 Pathway

For all peer reviewed studies on Protandim Nrf2 click on the link below:

BENEFITS

Why Take Antioxidants When You Can Make Them!

• Protection against oxidative stress

• Essential for normal metabolism

• Antioxidants help to reduce effects caused by free radical scavengers

• Assists in maintaining peak effort

• Helps body adapt to physically and mentally draining circumstances

• Helps maintain normal vitality/energy

• Helps support/maintain healthy immune function

• Relief of stress and mild anxiety

• Supports/maintains the body’s normal ability to cope during times of stress

• Helps release the feelings of fatigue caused by stress

Mighty Mitochondria and Nrf1 Activation

With Dr Gail Pearson

What is Protandim Nrf1 Synergizer?

The mitochondrial theory of aging is based on the fact that our mitochondria generate almost 95% of the energy required in our bodies. Unfortunately, our mitochondrial function declines over time or when stressed.

Protandim® NRF1 Synergizer is scientifically formulated to help your cells support mitochondrial function.*

NRF1 [nuclear factor erythroid 2-related factor] is a protein that regulates the expression of genes involved in mitochondrial DNA transcription, translation and repair. LifeVantage has found a way to activate NRF1 with a blend of natural ingredients that promote mitochondria production and repair to support healthy aging and cellular energy. Here's how it works:

Increases ATP: Higher ATP [Adenosine Triphosphate] levels increase energy for all your vital organs to support health at the cellular level. Higher ATP levels means more cellular energy—more cellular energy means your body works more efficiently. *

Boosts Mitochondria Production: Means your body functions more efficiently—improves cellular rejuvenation, supports heme production, supports brain function, cognitive health, and supports heart health. *

Activates NRF1 Protein: Wakes up the NRF1 protein to support mitochondrial biogenesis—the creation of new mitochondria. *

Reduce Oxidative Stress: Combined with Protandim Nrf2 Synergizer, natural antioxidants reduce oxidative stress to protect the mitochondria you have and promote cellular health. *

‘These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease’.

LIFE VANTAGE NRF1 SYNERGIZER WORKS ON THE CELLULAR LEVEL TO

• Increase cellular energy (ATP)*

• Improve performance through energy function*

• Enhance cellular health—cells function at their peak performance*

Protandim® Tri-Synergizer™*

Protandim Nrf2, NAD, and NRF1 Synergizers effectively reduce oxidative stress, support mitochondria function, increase sirtuin activity, and target cell signaling pathways to fight the effects of aging.

NAD

Recently, scientists have been sharing the immense importance of proteins called sirtuins. Studies are showing sirtuin activity comes with a cascade of health supporting benefits, including supporting a healthy vascular system, normal cholesterol levels already in the healthy range, supporting joint health, mental focus, balanced mood, motivation, energy, and much more. However, sirtuin activity declines as we age (≈60%). Researchers have discovered that sirtuin activity can be maintained through drastic caloric restriction (reducing calories by 40-60%). Obviously, this drastic approach runs the risk of nutrient deficiency and is not recommended without medical supervision. So, with the knowledge that sirtuin activation requires the molecule NAD, we went to work. Protandim® NAD SynergizerTM was specifically formulated to support NAD, supporting health, focus, energy, mental clarity, and mood.

PROBIO

GET SMART ABOUT PROBIOTICS

Uses ingredients to time release probiotics deep in your gastrointestinal tract to support optimal digestion—the smart way to take probiotics.

STRAIGHT TO THE GUT

Our whole digestive system is governed by a complex ecosystem of helpful and harmful bacteria. LifeVantage ProBio uses technology to deliver strains of healthy bacteria deep into your gut where they’re needed. Its 6 billion CFUs of friendly bacteria accompanied by Wellmune.